Mir-25 microRNA precursor family

mir-25
Identifiers
Symbolmir-25
RfamRF02020
miRBase family25
Other data
RNA typemicroRNA
Domain(s)Eukaryota;
PDB structuresPDBe

In molecular biology mir-25 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. mir-25 levels increase in human heart failure, and treatment with an anti-sense RNA molecule (antagomiR) was recently reported to halt disease progression and improves cardiac function in a mouse heart failure model.[1]

See also

  • MicroRNA

References

  1. ^ Wahlquist C, Jeong D, Rojas-Muñoz A, Kho C, Lee A, Mitsuyama S, van Mil A, Park WJ, Sluijter JP, Doevendans PA, Hajjar RJ, Mercola M (April 2014). "Inhibition of miR-25 improves cardiac contractility in the failing heart". Nature. 508 (7497): 531–5. doi:10.1038/nature13073. PMC 4131725. PMID 24670661.

Further reading

  • Kwok HH, Yue PY, Mak NK, Wong RN (August 2012). "Ginsenoside Rb₁ induces type I collagen expression through peroxisome proliferator-activated receptor-delta". Biochemical Pharmacology. 84 (4): 532–9. doi:10.1016/j.bcp.2012.05.023. PMID 22692056.
  • Nishida N, Nagahara M, Sato T, Mimori K, Sudo T, Tanaka F, Shibata K, Ishii H, Sugihara K, Doki Y, Mori M (June 2012). "Microarray analysis of colorectal cancer stromal tissue reveals upregulation of two oncogenic miRNA clusters". Clinical Cancer Research. 18 (11): 3054–70. doi:10.1158/1078-0432.CCR-11-1078. PMID 22452939.
  • Xu X, Chen Z, Zhao X, Wang J, Ding D, Wang Z, Tan F, Tan X, Zhou F, Sun J, Sun N, Gao Y, Shao K, Li N, Qiu B, He J (May 2012). "MicroRNA-25 promotes cell migration and invasion in esophageal squamous cell carcinoma". Biochemical and Biophysical Research Communications. 421 (4): 640–5. doi:10.1016/j.bbrc.2012.03.048. PMID 22450326.
  • Suh SS, Yoo JY, Nuovo GJ, Jeon YJ, Kim S, Lee TJ, Kim T, Bakàcs A, Alder H, Kaur B, Aqeilan RI, Pichiorri F, Croce CM (April 2012). "MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme". Proceedings of the National Academy of Sciences of the United States of America. 109 (14): 5316–21. doi:10.1073/pnas.1202465109. PMC 3325690. PMID 22431589.
  • Esposito F, Tornincasa M, Pallante P, Federico A, Borbone E, Pierantoni GM, Fusco A (May 2012). "Down-regulation of the miR-25 and miR-30d contributes to the development of anaplastic thyroid carcinoma targeting the polycomb protein EZH2". The Journal of Clinical Endocrinology and Metabolism. 97 (5): E710-8. doi:10.1210/jc.2011-3068. PMID 22399519.
  • Wu Q, Wang C, Lu Z, Guo L, Ge Q (July 2012). "Analysis of serum genome-wide microRNAs for breast cancer detection". Clinica Chimica Acta; International Journal of Clinical Chemistry. 413 (13–14): 1058–65. doi:10.1016/j.cca.2012.02.016. PMID 22387599.
  • Zhang S, Chen H, Zhao X, Cao J, Tong J, Lu J, Wu W, Shen H, Wei Q, Lu D (January 2013). "REV3L 3'UTR 460 T>C polymorphism in microRNA target sites contributes to lung cancer susceptibility". Oncogene. 32 (2): 242–50. doi:10.1038/onc.2012.32. PMID 22349819.
  • Ciuffreda L, Di Sanza C, Cesta Incani U, Eramo A, Desideri M, Biagioni F, Passeri D, Falcone I, Sette G, Bergamo P, Anichini A, Sabapathy K, McCubrey JA, Ricciardi MR, Tafuri A, Blandino G, Orlandi A, De Maria R, Cognetti F, Del Bufalo D, Milella M (June 2012). "The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms". Journal of Molecular Medicine. 90 (6): 667–79. doi:10.1007/s00109-011-0844-1. PMID 22215152. S2CID 17963454.
  • Zhang H, Zuo Z, Lu X, Wang L, Wang H, Zhu Z (February 2012). "MiR-25 regulates apoptosis by targeting Bim in human ovarian cancer". Oncology Reports. 27 (2): 594–8. doi:10.3892/or.2011.1530. PMID 22076535.
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  • Xie T, Liang J, Guo R, Liu N, Noble PW, Jiang D (May 2011). "Comprehensive microRNA analysis in bleomycin-induced pulmonary fibrosis identifies multiple sites of molecular regulation". Physiological Genomics. 43 (9): 479–87. doi:10.1152/physiolgenomics.00222.2010. PMC 3110895. PMID 21266501.
  • Zhang Z, O'Rourke JR, McManus MT, Lewandoski M, Harfe BD, Sun X (March 2011). "The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning". Developmental Biology. 351 (2): 254–65. doi:10.1016/j.ydbio.2011.01.005. PMC 3541530. PMID 21256124.
  • Scapoli L, Palmieri A, Lo Muzio L, Pezzetti F, Rubini C, Girardi A, Farinella F, Mazzotta M, Carinci F (2010). "MicroRNA expression profiling of oral carcinoma identifies new markers of tumor progression". International Journal of Immunopathology and Pharmacology. 23 (4): 1229–34. doi:10.1177/039463201002300427. hdl:11585/106742. PMID 21244772. S2CID 21890748.
  • Birks DK, Barton VN, Donson AM, Handler MH, Vibhakar R, Foreman NK (February 2011). "Survey of MicroRNA expression in pediatric brain tumors". Pediatric Blood & Cancer. 56 (2): 211–6. doi:10.1002/pbc.22723. PMID 21157891. S2CID 12955063.
  • Li LM, Hu ZB, Zhou ZX, Chen X, Liu FY, Zhang JF, Shen HB, Zhang CY, Zen K (December 2010). "Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBV-positive hepatocarcinoma". Cancer Research. 70 (23): 9798–807. doi:10.1158/0008-5472.CAN-10-1001. PMID 21098710.
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  • Fu Y, Zhang Y, Wang Z, Wang L, Wei X, Zhang B, Wen Z, Fang H, Pang Q, Yi F (2010). "Regulation of NADPH oxidase activity is associated with miRNA-25-mediated NOX4 expression in experimental diabetic nephropathy". American Journal of Nephrology. 32 (6): 581–9. doi:10.1159/000322105. PMID 21071935. S2CID 31810215.
  • Kumar M, Lu Z, Takwi AA, Chen W, Callander NS, Ramos KS, Young KH, Li Y (February 2011). "Negative regulation of the tumor suppressor p53 gene by microRNAs". Oncogene. 30 (7): 843–53. doi:10.1038/onc.2010.457. PMC 3021102. PMID 20935678.
  • Dacic S, Kelly L, Shuai Y, Nikiforova MN (December 2010). "miRNA expression profiling of lung adenocarcinomas: correlation with mutational status". Modern Pathology. 23 (12): 1577–82. doi:10.1038/modpathol.2010.152. PMID 20818338.
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  • Cheever A, Blackwell E, Ceman S (August 2010). "Fragile X protein family member FXR1P is regulated by microRNAs". RNA. 16 (8): 1530–9. doi:10.1261/rna.2022210. PMC 2905753. PMID 20519410.
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  • Wang Y, Li Z, He C, Wang D, Yuan X, Chen J, Jin J (March 2010). "MicroRNAs expression signatures are associated with lineage and survival in acute leukemias". Blood Cells, Molecules & Diseases. 44 (3): 191–7. doi:10.1016/j.bcmd.2009.12.010. PMC 2829339. PMID 20110180.
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  • Page for mir-25 microRNA precursor family at Rfam
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