Mir-497 microRNA precursor family

mir-497
Identifiers
Symbol	mir-497
Rfam	RF00793
miRBase family	MIPF0000231
Other data
RNA type	microRNA
Domain(s)	Eukaryota;
PDB structures	PDBe

In molecular biology mir-497 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.

References

Guo ST, Jiang CC, Wang GP, Li YP, Wang CY, Guo XY, Yang RH, Feng Y, Wang FH, Tseng HY, Thorne RF, Jin L, Zhang XD (April 2013). "MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer". Oncogene. 32 (15): 1910–20. doi:10.1038/onc.2012.214. PMC 3630484. PMID 22710713.
Yang C, Wang C, Chen X, Chen S, Zhang Y, Zhi F, Wang J, Li L, Zhou X, Li N, Pan H, Zhang J, Zen K, Zhang CY, Zhang C (January 2013). "Identification of seven serum microRNAs from a genome-wide serum microRNA expression profile as potential noninvasive biomarkers for malignant astrocytomas". International Journal of Cancer. 132 (1): 116–27. doi:10.1002/ijc.27657. PMID 22674182.
Lajer CB, Garnæs E, Friis-Hansen L, Norrild B, Therkildsen MH, Glud M, Rossing M, Lajer H, Svane D, Skotte L, Specht L, Buchwald C, Nielsen FC (April 2012). "The role of miRNAs in human papilloma virus (HPV)-associated cancers: bridging between HPV-related head and neck cancer and cervical cancer". British Journal of Cancer. 106 (9): 1526–34. doi:10.1038/bjc.2012.109. PMC 3341860. PMID 22472886.
Luense LJ, Veiga-Lopez A, Padmanabhan V, Christenson LK (December 2011). "Developmental programming: gestational testosterone treatment alters fetal ovarian gene expression". Endocrinology. 152 (12): 4974–83. doi:10.1210/en.2011-1182. PMC 3384818. PMID 22009729.
Yadav S, Pandey A, Shukla A, Talwelkar SS, Kumar A, Pant AB, Parmar D (October 2011). "miR-497 and miR-302b regulate ethanol-induced neuronal cell death through BCL2 protein and cyclin D2". The Journal of Biological Chemistry. 286 (43): 37347–57. doi:10.1074/jbc.M111.235531. PMC 3199482. PMID 21878650.
Özata DM, Caramuta S, Velázquez-Fernández D, Akçakaya P, Xie H, Höög A, Zedenius J, Bäckdahl M, Larsson C, Lui WO (October 2011). "The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma". Endocrine-Related Cancer. 18 (6): 643–55. doi:10.1530/ERC-11-0082. PMC 3201061. PMID 21859927.
Xu X, Jia R, Zhou Y, Song X, Wang J, Qian G, Ge S, Fan X (May 2011). "Microarray-based analysis: identification of hypoxia-regulated microRNAs in retinoblastoma cells". International Journal of Oncology. 38 (5): 1385–93. doi:10.3892/ijo.2011.961. PMID 21373755.
Balatti V, Maniero S, Ferracin M, Veronese A, Negrini M, Ferrocci G, Martini F, Tognon MG (May 2011). "MicroRNAs dysregulation in human malignant pleural mesothelioma". Journal of Thoracic Oncology. 6 (5): 844–51. doi:10.1097/JTO.0b013e31820db125. PMID 21358347.
Li D, Zhao Y, Liu C, Chen X, Qi Y, Jiang Y, Zou C, Zhang X, Liu S, Wang X, Zhao D, Sun Q, Zeng Z, Dress A, Lin MC, Kung HF, Rui H, Liu LZ, Mao F, Jiang BH, Lai L (April 2011). "Analysis of MiR-195 and MiR-497 expression, regulation and role in breast cancer". Clinical Cancer Research. 17 (7): 1722–30. doi:10.1158/1078-0432.CCR-10-1800. PMID 21350001.
Zhu W, Zhu D, Lu S, Wang T, Wang J, Jiang B, Shu Y, Liu P (March 2012). "miR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2". Medical Oncology. 29 (1): 384–91. doi:10.1007/s12032-010-9797-4. PMID 21258880. S2CID 26205260.
Rink C, Khanna S (May 2011). "MicroRNA in ischemic stroke etiology and pathology". Physiological Genomics. 43 (10): 521–8. doi:10.1152/physiolgenomics.00158.2010. PMC 3110894. PMID 20841499.
Finnerty JR, Wang WX, Hébert SS, Wilfred BR, Mao G, Nelson PT (September 2010). "The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases". Journal of Molecular Biology. 402 (3): 491–509. doi:10.1016/j.jmb.2010.07.051. PMC 2978331. PMID 20678503.
Wald AI, Hoskins EE, Wells SI, Ferris RL, Khan SA (April 2011). "Alteration of microRNA profiles in squamous cell carcinoma of the head and neck cell lines by human papillomavirus". Head & Neck. 33 (4): 504–12. doi:10.1002/hed.21475. PMC 3080748. PMID 20652977.
Lehmann U, Streichert T, Otto B, Albat C, Hasemeier B, Christgen H, Schipper E, Hille U, Kreipe HH, Länger F (March 2010). "Identification of differentially expressed microRNAs in human male breast cancer". BMC Cancer. 10: 109. doi:10.1186/1471-2407-10-109. PMC 2850898. PMID 20331864.
Lindberg RL, Hoffmann F, Mehling M, Kuhle J, Kappos L (March 2010). "Altered expression of miR-17-5p in CD4+ lymphocytes of relapsing-remitting multiple sclerosis patients". European Journal of Immunology. 40 (3): 888–98. doi:10.1002/eji.200940032. PMID 20148420. S2CID 205786377.
Yin KJ, Deng Z, Huang H, Hamblin M, Xie C, Zhang J, Chen YE (April 2010). "miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia". Neurobiology of Disease. 38 (1): 17–26. doi:10.1016/j.nbd.2009.12.021. PMC 2837803. PMID 20053374.
Olsen L, Klausen M, Helboe L, Nielsen FC, Werge T (October 2009). Preiss T (ed.). "MicroRNAs show mutually exclusive expression patterns in the brain of adult male rats". PLOS ONE. 4 (10): e7225. doi:10.1371/journal.pone.0007225. PMC 2752988. PMID 19806225.
Guo J, Miao Y, Xiao B, Huan R, Jiang Z, Meng D, Wang Y (April 2009). "Differential expression of microRNA species in human gastric cancer versus non-tumorous tissues". Journal of Gastroenterology and Hepatology. 24 (4): 652–7. doi:10.1111/j.1440-1746.2008.05666.x. PMID 19175831. S2CID 32936687.
Yan LX, Huang XF, Shao Q, Huang MY, Deng L, Wu QL, Zeng YX, Shao JY (November 2008). "MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis". RNA. 14 (11): 2348–60. doi:10.1261/rna.1034808. PMC 2578865. PMID 18812439.
Flavin RJ, Smyth PC, Laios A, O'Toole SA, Barrett C, Finn SP, Russell S, Ring M, Denning KM, Li J, Aherne ST, Sammarae DA, Aziz NA, Alhadi A, Sheppard BL, Lao K, Sheils OM, O'Leary JJ (February 2009). "Potentially important microRNA cluster on chromosome 17p13.1 in primary peritoneal carcinoma". Modern Pathology. 22 (2): 197–205. doi:10.1038/modpathol.2008.135. PMID 18677302.