UGT1A8 |
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Identifiers |
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Aliases | UGT1A8, UDPGT, UDPGT 1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H, UDP glucuronosyltransferase family 1 member A8, UGT1-01, UGT-1A, UGT1.1, UGT1A, hUG-BR1, UGT1, GNT1, UGT1A1, UDPGT 1-1 |
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External IDs | OMIM: 606433; MGI: 3576092; HomoloGene: 133281; GeneCards: UGT1A8; OMA:UGT1A8 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 2 (human)[1] |
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| Band | 2q37.1 | Start | 233,617,633 bp[1] |
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End | 233,773,300 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 1 (mouse)[2] |
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| Band | 1|1 D | Start | 87,998,522 bp[2] |
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End | 88,146,719 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - mucosa of transverse colon
- rectum
- gallbladder
- olfactory zone of nasal mucosa
- duodenum
- urinary bladder
- epithelium of colon
- right lobe of liver
- islet of Langerhans
- appendix
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| Top expressed in | - hepatobiliary system
- liver
- duodenum
- embryo
- colon
- renal cortex
- proximal tubule
- stomach
- human kidney
- ileum
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - transferase activity
- enzyme inhibitor activity
- retinoic acid binding
- hexosyltransferase activity
- protein homodimerization activity
- glycosyltransferase activity
- glucuronosyltransferase activity
- fatty acid binding
- steroid binding
- protein heterodimerization activity
- enzyme binding
- UDP-glycosyltransferase activity
| Cellular component | - integral component of membrane
- endoplasmic reticulum membrane
- membrane
- intracellular membrane-bounded organelle
- endoplasmic reticulum
| Biological process | - steroid metabolic process
- coumarin metabolic process
- negative regulation of steroid metabolic process
- retinoic acid metabolic process
- negative regulation of cellular glucuronidation
- fatty acid metabolic process
- cellular glucuronidation
- flavonoid glucuronidation
- xenobiotic glucuronidation
- flavone metabolic process
- metabolism
- negative regulation of glucuronosyltransferase activity
- negative regulation of fatty acid metabolic process
- negative regulation of catalytic activity
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 2: 233.62 – 233.77 Mb | Chr 1: 88 – 88.15 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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