Lysine N-acetyltransferase
Class of enzymes
lysine N-acetyltransferase | |||||||||
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Lysine N-acetyltransferase (EIS) hexamer, Mycobacterium tuberculosis | |||||||||
Identifiers | |||||||||
EC no. | 2.3.1.32 | ||||||||
CAS no. | 37257-12-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a lysine N-acetyltransferase (EC 2.3.1.32) is an enzyme that catalyzes the chemical reaction
- acetyl phosphate + L-lysine phosphate + N6-acetyl-L-lysine
Thus, the two substrates of this enzyme are acetyl phosphate and L-lysine, whereas its two products are phosphate and N6-acetyl-L-lysine.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-phosphate:L-lysine N6-acetyltransferase. Other names in common use include lysine acetyltransferase, and acetyl-phosphate:L-lysine 6-N-acetyltransferase. This enzyme participates in lysine degradation.
References
- PAIK WK, KIM S (1964). "ENZYMIC SYNTHESIS OF EPSILON-N-ACETYL-L-LYSINE". Arch. Biochem. Biophys. 108 (2): 221–9. doi:10.1016/0003-9861(64)90379-0. PMID 14240571.
- v
- t
- e
- acetyltransferases: Acetyl-Coenzyme A acetyltransferase
- N-Acetylglutamate synthase
- Choline acetyltransferase
- Dihydrolipoyl transacetylase
- Acetyl-CoA C-acyltransferase
- Beta-galactoside transacetylase
- Chloramphenicol acetyltransferase
- N-acetyltransferase
- Histone acetyltransferase
- Citrate synthase
- Decylcitrate synthase
- Citrate (Re)-synthase
- Decylhomocitrate synthase
- 2-methylcitrate synthase
- 2-ethylmalate synthase
- 3-ethylmalate synthase
- ATP citrate lyase
- Malate synthase
- HMG-CoA synthase
- 2-hydroxyglutarate synthase
- 3-propylmalate synthase
- 2-isopropylmalate synthase
- Homocitrate synthase
- Sulfoacetaldehyde acetyltransferase