Narasin

Chemical compound
  • QP51BB04 (WHO) QP51BB54 (WHO)
Identifiers
  • (2R)-2-[(2R,3S,5S,6R)-6-[(1S,2S,3S,5R)-5- [(2S,5S,7R,9S,10S,12R,15R)-2-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyl-2-tetrahydropyranyl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-2-hydroxy-1,3-dimethyl-4-oxoheptyl]-3,5-dimethyl-2-tetrahydropyranyl]butanoic acid
CAS Number
  • 55134-13-9 checkY
PubChem CID
  • 65452
ChemSpider
  • 58911
UNII
  • DZY9VU539P
CompTox Dashboard (EPA)
  • DTXSID2046707 Edit this at Wikidata
ECHA InfoCard100.122.892 Edit this at WikidataChemical and physical dataFormulaC43H72O11Molar mass765.038 g·mol−13D model (JSmol)
  • Interactive image
  • O=C([C@@H](C)[C@@H](O)[C@H](C)[C@]5([H])O[C@]([C@@H](CC)C(O)=O)([H])[C@@H](C)C[C@@H]5C)[C@H](CC)[C@@]1([H])O[C@@]2(O[C@@]3(CC[C@]([C@]4([H])O[C@@H](C)[C@@](O)(CC)CC4)(C)O3)[C@H](O)C=C2)[C@H](C)C[C@@H]1C
InChI
  • InChI=1S/C43H72O11/c1-12-30(35(46)27(8)34(45)28(9)36-23(4)21-24(5)37(51-36)31(13-2)39(47)48)38-25(6)22-26(7)42(52-38)18-15-32(44)43(54-42)20-19-40(11,53-43)33-16-17-41(49,14-3)29(10)50-33/h15,18,23-34,36-38,44-45,49H,12-14,16-17,19-22H2,1-11H3,(H,47,48)/t23-,24-,25-,26+,27-,28-,29-,30-,31+,32+,33+,34+,36+,37+,38-,40-,41+,42-,43-/m0/s1
  • Key:VHKXXVVRRDYCIK-CWCPJSEDSA-N
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Narasin is a coccidiostat and antibacterial agent.[1][2] It is a derivative of salinomycin with an additional methyl group. Narasin is produced by fermentation of a strain of Streptomyces aureofaciens.[3]

References

  1. ^ Gerhold RW, Fuller AL, Lollis L, Parr C, McDougald LR (March 2011). "The efficacy of anticoccidial products against Eimeria spp. in northern bobwhites". Avian Diseases. 55 (1): 59–64. doi:10.1637/9572-101310-Reg.1. PMID 21500637. S2CID 30943649.
  2. ^ Fitzgerald PR, Mansfield ME (July 1989). "Effects of inoculations with Eimeria zuernii on young calves treated with decoquinate or narasin with or without dexamethasone". American Journal of Veterinary Research. 50 (7): 1056–1059. PMID 2774323.
  3. ^ Anadón A, Martínez-Larrañaga MR (2014). "Veterinary Drugs Residues: Coccidiostats". Encyclopedia of Food Safety. pp. 63–75. doi:10.1016/B978-0-12-378612-8.00246-8. ISBN 9780123786135.
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