KDM3A |
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Identifiers |
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Aliases | KDM3A, JHDM2A, JHMD2A, JMJD1, JMJD1A, TSGA, lysine demethylase 3A |
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External IDs | OMIM: 611512; MGI: 98847; HomoloGene: 10196; GeneCards: KDM3A; OMA:KDM3A - orthologs |
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Gene location (Human) |
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![Chromosome 2 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Ideogram_human_chromosome_2.svg/300px-Ideogram_human_chromosome_2.svg.png) | Chr. | Chromosome 2 (human)[1] |
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| Band | 2p11.2 | Start | 86,440,647 bp[1] |
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End | 86,492,716 bp[1] |
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Gene location (Mouse) |
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![Chromosome 6 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Ideogram_house_mouse_chromosome_6.svg/260px-Ideogram_house_mouse_chromosome_6.svg.png) | Chr. | Chromosome 6 (mouse)[2] |
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| Band | 6|6 C1 | Start | 71,565,956 bp[2] |
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End | 71,609,974 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - secondary oocyte
- Achilles tendon
- sperm
- ventricular zone
- sural nerve
- skin of thigh
- skin of abdomen
- skin of hip
- left testis
- right testis
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| Top expressed in | - spermatocyte
- spermatid
- tail of embryo
- genital tubercle
- ventricular zone
- Gonadal ridge
- seminiferous tubule
- neural layer of retina
- left lung lobe
- ganglionic eminence
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - iron ion binding
- DNA-binding transcription factor activity
- dioxygenase activity
- metal ion binding
- androgen receptor binding
- oxidoreductase activity
- histone demethylase activity
- transcription cis-regulatory region binding
- chromatin DNA binding
- histone H3-methyl-lysine-9 demethylase activity
- protein binding
- RNA polymerase II core promoter sequence-specific DNA binding
| Cellular component | - cytoplasm
- membrane
- nucleoplasm
- nucleus
- chromatin
| Biological process | - androgen receptor signaling pathway
- cell differentiation
- regulation of transcription, DNA-templated
- histone H3-K9 dimethylation
- regulation of stem cell differentiation
- regulation of stem cell population maintenance
- transcription, DNA-templated
- positive regulation of transcription, DNA-templated
- spermatogenesis
- hormone-mediated signaling pathway
- negative regulation of histone H3-K9 methylation
- regulation of gene expression
- formaldehyde biosynthetic process
- spermatid nucleus elongation
- positive regulation of transcription by RNA polymerase II
- histone H3-K9 demethylation
- cellular response to leukemia inhibitory factor
- chromatin organization
- positive regulation of cold-induced thermogenesis
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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NM_001038695 NM_173001 NM_001362200 NM_001362201 |
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RefSeq (protein) | | |
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NP_001033784 NP_766589 NP_001349129 NP_001349130 |
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Location (UCSC) | Chr 2: 86.44 – 86.49 Mb | Chr 6: 71.57 – 71.61 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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