E2F7 |
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Identifiers |
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Aliases | E2F7, E2F transcription factor 7 |
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External IDs | OMIM: 612046; MGI: 1289147; HomoloGene: 18685; GeneCards: E2F7; OMA:E2F7 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 12 (human)[1] |
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| Band | 12q21.2 | Start | 77,021,248 bp[1] |
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End | 77,065,569 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 10 (mouse)[2] |
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| Band | 10 D1|10 57.74 cM | Start | 110,581,300 bp[2] |
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End | 110,623,245 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - ventricular zone
- thymus
- gonad
- ganglionic eminence
- testicle
- secondary oocyte
- stromal cell of endometrium
- mucosa of ileum
- bone marrow cells
- pancreatic ductal cell
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| Top expressed in | - otic vesicle
- hand
- primitive streak
- fossa
- tail of embryo
- condyle
- yolk sac
- genital tubercle
- abdominal wall
- mandibular prominence
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - DNA binding
- RNA polymerase II transcription regulatory region sequence-specific DNA binding
- transcription corepressor activity
- protein binding
- DNA-binding transcription repressor activity, RNA polymerase II-specific
- identical protein binding
- DNA-binding transcription factor activity
- DNA-binding transcription factor activity, RNA polymerase II-specific
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
- cis-regulatory region sequence-specific DNA binding
- DNA-binding transcription activator activity, RNA polymerase II-specific
- transcription factor binding
- sequence-specific DNA binding
| Cellular component | - transcription regulator complex
- nucleus
- nucleoplasm
- nuclear speck
- RNA polymerase II transcription regulator complex
| Biological process | - trophoblast giant cell differentiation
- regulation of transcription, DNA-templated
- chorionic trophoblast cell differentiation
- negative regulation of transcription involved in G1/S transition of mitotic cell cycle
- placenta development
- DNA damage response, signal transduction by p53 class mediator
- hepatocyte differentiation
- negative regulation of transcription by RNA polymerase II
- transcription, DNA-templated
- cellular response to DNA damage stimulus
- negative regulation of G1/S transition of mitotic cell cycle
- cell cycle
- negative regulation of cytokinesis
- positive regulation of DNA endoreduplication
- positive regulation of transcription by RNA polymerase II
- sprouting angiogenesis
- DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
- negative regulation of cell population proliferation
- regulation of cell cycle
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 12: 77.02 – 77.07 Mb | Chr 10: 110.58 – 110.62 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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