Citiolone
Chemical compound
- A05BA04 (WHO)
- (RS)-N-(2-Oxothiolan-3-yl)acetamide
- 1195-16-0 Y
- 14520
- 13864 Y
- 70JKL15MUH
- D07105 Y
- ChEMBL2104457 N
- DTXSID0045888
InChI
- InChI=1S/C6H9NO2S/c1-4(8)7-5-2-3-10-6(5)9/h5H,2-3H2,1H3,(H,7,8) Y
- Key:NRFJZTXWLKPZAV-UHFFFAOYSA-N Y
Citiolone is a drug used in liver therapy.
It is a derivative of the amino acid cysteine.[1] Citilone has also been studied with regards to hypothermia due to it being a hydroxyl free radical scavenger. The drug has been shown to protect hamster cells subjected to temperature conditions of 8-25 °C.[2]
References
- ^ de Barrio M, Tornero P, Prieto A, Sainza T, Zubeldia JM, Herrero T (1997). "Recurrent fixed drug eruption caused by citiolone". Journal of Investigational Allergology & Clinical Immunology. 7 (3): 193–194. PMID 9252880.
- ^ Kruuv J, Glofcheski DJ (June 1993). "Further evidence for two modes of hypothermia damage". Cryobiology. 30 (3): 313–321. doi:10.1006/cryo.1993.1030. PMID 8370318.
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