Spo11 |
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識別號 |
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别名 | SPO11;, CT35, SPATA43, TOPVIA, initiator of meiotic double stranded breaks, SPO11 initiator of meiotic double stranded breaks, Meiotic recombination, Spo11, Meiotic_Spo11, IPR013048, Spo11, TOPOVIA |
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外部ID | OMIM:605114 MGI:1349669 HomoloGene:6059 GeneCards:SPO11 |
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基因位置(小鼠) |
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![小鼠2号染色体](//upload.wikimedia.org/wikipedia/commons/thumb/b/bb/Ideogram_house_mouse_chromosome_2.svg/260px-Ideogram_house_mouse_chromosome_2.svg.png) | 染色体 | 小鼠2号染色体[2] |
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| 基因座 | 2 H3|2 95.64 cM | 起始 | 172,819,493 bp[2] |
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终止 | 172,835,369 bp[2] |
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基因本體 |
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分子功能 | • 金屬離子結合 • 催化活性 • 水解酶活性 • ATP結合 • 血浆蛋白结合 • isomerase activity • DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity • endodeoxyribonuclease activity, producing 3'-phosphomonoesters • DNA结合
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細胞組分 | • 染色体 • 端粒 • 细胞核 • nuclear chromosome
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生物學過程 | • protein localization to chromosome • 雌配子发生 • meiotic telomere clustering • male meiosis I • DNA代谢过程 • DNA catabolic process, endonucleolytic • 卵子发生 • homologous chromosome pairing at meiosis • 減數分裂 • synaptonemal complex assembly • 精子发生 • spermatid development • ovarian follicle development • meiotic DNA double-strand break processing • meiotic DNA double-strand break formation • reciprocal meiotic recombination • double-strand break repair involved in meiotic recombination
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Sources:Amigo / QuickGO |
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直系同源 |
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物種 | 人類 | 小鼠 |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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mRNA序列 | | |
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NM_001083959 NM_001083960 NM_012046 NM_001305434 |
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蛋白序列 | | |
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NP_001077428 NP_001077429 NP_001292363 NP_036176 |
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基因位置(UCSC) | Chr 20: 57.33 – 57.34 Mb | Chr 2: 172.82 – 172.84 Mb |
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PubMed查找 | [3] | [4] |
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維基數據 |
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