前维生素D3
Previtamin D3 | |
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IUPAC名 Previtamin D3 | |
识别 | |
CAS号 | 1173-13-3 ![]() 17592-07-3 ![]() |
PubChem | 86590 6178113((E)-en) 25245851((1S)-1-ol, (Z)-en, (2R)-2-yl) 11485943((1S)-1-ol, (E)-en, (1R,7aR)-7a-meth,-1-hept, (2R)-2-yl) 11199982((1S)-1-ol, (Z)-en, (1R,7aR)-7a-meth,-1-hept, (2R)-2-yl) |
ChemSpider | 78098, 4832524 (E)-en, 9660762 (1S)-1-ol, (E)-en, (1R,7aR)-7a-meth,-1-hept, (2R)-2-yl, 9375051 (1S)-1-ol, (Z)-en, (1R,7aR)-7a-meth,-1-hept, (2R)-2-yl |
SMILES |
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EINECS | 241-561-3 |
MeSH | Previtamin+D(3) |
性质 | |
化学式 | C27H44O |
摩尔质量 | 384.64 g·mol−1 |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
维生素D3原(又稱:前維生素D3,英語:Previtamin D3)是胆钙化醇(维生素D3)合成的中间产物,由皮肤表皮中的7-脱氢胆固醇在紫外线(主要是295nm - 300nm 的UV-B)照射下开环生成[1][2][3][4]。
参考文献
- ^ MacLaughlin JA, Anderson RR, Holick MF. Spectral character of sunlight modulates photosynthesis of previtamin D3 and its photoisomers in human skin. Science. May 1982, 216 (4549): 1001–3. Bibcode:1982Sci...216.1001M. PMID 6281884. doi:10.1126/science.6281884.
- ^ Webb AR. Who, what, where and when-influences on cutaneous vitamin D synthesis. Progress in Biophysics and Molecular Biology. September 2006, 92 (1): 17–25. PMID 16766240. doi:10.1016/j.pbiomolbio.2006.02.004.
- ^ Pope SJ, Holick MF, Mackin S, Godar DE. Action spectrum conversion factors that change erythemally weighted to previtamin D3-weighted UV doses. Photochemistry and Photobiology. 2008, 84 (5): 1277–83. PMID 18513232. doi:10.1111/j.1751-1097.2008.00373.x.
- ^ Sayre RM, Dowdy JC. Darkness at noon: sunscreens and vitamin D3. Photochemistry and Photobiology. 2007, 83 (2): 459–63. PMID 17115796. doi:10.1562/2006-06-29-RC-956.
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