Inozitol-1,4-bisfosfatna 1-fosfataza

Inozitol-1,4-bisfosfatna 1-fosfataza
Identifikatori
EC broj3.1.3.57
CAS broj111694-13-4&title= 111070-17-8, 111694-13-4
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum
Pretraga
PMCčlanci
PubMedčlanci
NCBIproteini

Inozitol-1,4-bisfosfatna 1-fosfataza (EC 3.1.3.57, inozitol-polifosfatna 1-fosfataza) je enzim sa sistematskim imenom 1D-mio-inozitol-1,4-bisfosfat 1-fosfohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

1D-mio-inozitol 1,4-bisfosfat + H2O {\displaystyle \rightleftharpoons } 1D-mio-inozitol 4-fosfat + fosfat

Ovaj enzim deluje na inozitol 1,4-bisfosfat i inozitol 1,3,4-trisfosfat (formira inozitol 3,4-bisfosfat) sa sličnim Vmax vrednostima za oba supstrata.

Reference

  1. ^ Berridge, M.J., Dawson, R.M.C., Downes, C.P., Heslop, J.P. and Irvine, R.F. (1983). „Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides”. Biochem. J. 212: 473—482. PMID 6309146. CS1 одржавање: Вишеструка имена: списак аутора (веза)
  2. ^ Connolly, T.M., Bansal, V.S., Bross, T.E., Irvine, R.F. and Majerus, P.W. (1987). „The metabolism of tris- and tetraphosphates of inositol by 5-phosphomonoesterase and 3-kinase enzymes”. J. Biol. Chem. 262: 2146—2149. PMID 3029066. CS1 одржавање: Вишеструка имена: списак аутора (веза)
  3. ^ Inhorn, R.C. & Majerus, P.W. (1987). „Inositol polyphosphate 1-phosphatase from calf brain. Purification and inhibition by Li+, Ca2+, and Mn2+”. J. Biol. Chem. 262: 15946—15952. PMID 2824473. 

Literatura

  • Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 
  • William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605. 

Spoljašnje veze

  • Inositol-1,4-bisphosphate+1-phosphatase на US National Library of Medicine Medical Subject Headings (MeSH)
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TemeTipovi
  • B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
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