Forbol-diestarska hidrolaza

Forbol-diestarska hidrolaza
Identifikatori
EC broj3.1.1.51
CAS broj81181-74-0
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IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
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Forbol-diestarska hidrolaza (EC 3.1.1.51, diacilforbatna 12-hidrolaza, diacilforbatna 12-hidrolaza, forbol-12,13-diestar 12-estarska hidrolaza, PDEH) je enzim sa sistematskim imenom 12,13-diacilforbat 12-acilhidrolaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

forbol 12,13-dibutanoat + H2O {\displaystyle \rightleftharpoons } forbol 13-butanoat + butanoat

Ovaj enzim hidrolizuje 12-estarsku vezu u mnoštvu 12,13-diacilforbola.

Reference

  1. ^ Shoyab, M., Warren, T.C. and Todaro, G.J. (1981). „Isolation and characterization of an ester hydrolase active on phorbol diesters from murine liver”. J. Biol. Chem. 256: 12529—12534. PMID 6946062. CS1 одржавање: Вишеструка имена: списак аутора (веза)

Literatura

  • Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 

Spoljašnje veze

  • Phorbol-diester+hydrolase на US National Library of Medicine Medical Subject Headings (MeSH)
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TemeTipovi
  • B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
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