Metionin adenoziltransferaza
| Metionin adenoziltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Tetramer metionin adenoziltransferaze 2 (čovjek) | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.5.1.6 | ||||||||
| CAS broj | 9012-52-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Metionin adenoziltransferaza (EC 2.5.1.6, adenozilmetionin sintetaza, ATP-metionin adenoziltransferaza, metionin S-adenoziltransferaza, metionin-aktivacioni enzim, S-adenozil-L-metionin sintetaza, S-adenozilmetionin sintaza, S-adenozilmetionin sintetaza, AdoMet sintetaza) je enzim sa sistematskim imenom ATP:L-metionin S-adenoziltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + L-metionin +H2O fosfat + difosfat + S-adenozil-L-metionin
Reference
- ↑ Cantoni, G.L. (1953). „S-Adenosylmethionine: A new intermediate formed enzymatically from L-methionine and adenosinetriphosphate”. J. Biol. Chem. 204: 403-416. PMID 13084611.
- ↑ Cantoni, G.L. and Durell, J. (1957). „Activation of methionine for transmethylation. II. The methionine-activating enzyme: studies on the mechanism of reaction”. J. Biol. Chem. 225: 1033-1048. PMID 13416303.
- ↑ Mudd, S.H. and Cantoni, G.L. (1958). „Activation of methionine for transmethylation. III. The methionine-activating enzyme of bakers' yeast”. J. Biol. Chem. 231: 481-492. PMID 13538985.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH Methionine+adenosyltransferase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
