Membranski transkripcioni faktor peptidaza, mesto 1
Membranski transkripcioni faktor peptidaza, mesto 1 | |
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Identifikatori | |
Simbol | MBTPS1 |
Alt. simboli | S1P |
Entrez | 8720 |
Hugo | 15456 |
OMIM | 603355 |
RefSek | NM_003791 |
UniProt | Q14703 |
Drugi podaci | |
EC broj | 3.4.21.112 |
Lokus | Hrom. 16 q24 |
Membranski transkripcioni faktor peptidaza, mesto 1, takođe poznata kao Mesto-1 proteaza (engl. Site-1 Protease - S1P), je enzim (EC 3.4.21.112) kodiran MBTPS1 genom koji koji odseca petlju endoplazmatičnog retikuluma od transkripcionog faktora vezujućeg proteina sterolnog regulatornog elementa (SREBP).[1][2]
Povezano
- S2P
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- ↑ Brown MS, Goldstein JL (1999). „A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood”. Proc. Natl. Acad. Sci. U.S.A. 96 (20): 11041–8. DOI:10.1073/pnas.96.20.11041. PMC 34238. PMID 10500120.
- ↑ Nakajima T, Iwaki K, Kodama T, Inazawa J, Emi M (2000). „Genomic structure and chromosomal mapping of the human site-1 protease (S1P) gene”. J. Hum. Genet. 45 (4): 212–7. DOI:10.1007/s100380070029. PMID 10944850.
Spoljašnje veze
- MeSH site-1+protease
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6