Cijanurinsko kiselinska amidohidrolaza
Cijanurinsko kiselinska amidohidrolaza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.5.2.15 | ||||||||
CAS broj | 132965-78-7 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Cijanurinsko kiselinska amidohidrolaza (EC 3.5.2.15, AtzD) je enzim sa sistematskim imenom cijanurinska kiselina amidohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- cijanurinska kiselina + H2O biuret + CO2
Zajedno sa EC 3.5.1.54 (alofanatnom hidrolazom) i EC 3.5.1.84 (biuretnom amidohidrolazom), ovaj enzim formira deo cijanurinsko kiselinskog metaboličkog puta.
Reference
- ↑ Eaton, R.W. and Karns, J.S. (1991). „Cloning and comparison of the DNA encoding ammelide aminohydrolase and cyanuric acid amidohydrolase from three s-triazine-degrading bacterial strains”. J. Bacteriol. 173: 1363-1366. PMID 1991731.
- ↑ Eaton, R.W. and Karns, J.S. (1991). „Cloning and analysis of s-triazine catabolic genes from Pseudomonas sp. strain NRRLB-12227”. J. Bacteriol. 173: 1215-1222. PMID 1846859.
- ↑ Karns, J.S. (1999). „Gene sequence and properties of an s-triazine ring-cleavage enzyme from Pseudomonas sp. strain NRRLB-12227”. Appl. Environ. Microbiol. 65: 3512-3517. PMID 10427042.
- ↑ Fruchey, I., Shapir, N., Sadowsky, M.J. and Wackett, L.P. (2003). „On the origins of cyanuric acid hydrolase: purification, substrates, and prevalence of AtzD from Pseudomonas sp. strain ADP”. Appl. Environ. Microbiol. 69: 3653-3657. PMID 12788776.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH Cyanuric+acid+amidohydrolase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6