Cerevisin
| Cerevisin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.48 | ||||||||
| CAS broj | 37288-81-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Cerevisin (EC 3.4.21.48, proteinaza yscB, proteinaza B pekarskog kvasca, proteinaza pivskog kvasca, peptidaza beta) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Hidroliza proteina sa širokom specifičnošću, i Bz-Arg-OEt Ac-Tyr-Oet. Ne dolazi do hidrolize peptidnih amida
Ovaj enzim je izolovan iz kvasca Saccharomyces cerevisiae.
Reference
- ↑ Félix, F. and Brouillet, N. (1966). „Purification et proprietes de deux peptidases de levure de brasserie”. Biochim. Biophys. Acta 122: 127-144. PMID 4961236.
- ↑ Kominami, E., Hoffschulte, H., Leuschel, L., Maier, K. and Holzer, H. (1981). „The substrate specificity of proteinase B from baker’s yeast”. Biochim. Biophys. Acta 661: 136-141. PMID 7028121.
- ↑ Farley, P.C., Shepherd, M.G. and Sullivan, P.A. (1986). „The purification and properties of yeast proteinase B from Candida albicans”. Biochem. J. 236: 177-184. PMID 3539100.
- ↑ Moehle, C.M., Tizard, R., Lemmon, S.K., Smart, J. and Jones, E.W. (1987). „Protease B of the lysosome like vacuole of the yeast Saccharomyces cerevisiae is homologous to the subtilisin family of serine proteases”. Mol. Cell. Biol. 7: 4390-4399. PMID 3325823.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH Cerevisin
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
