1,2-Alfa-L-fukozidaza
| 1,2-Alfa-L-fukozidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.2.1.63 | ||||||||
| CAS broj | 37288-45-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
1,2-Alfa-L-fukozidaza (EC 3.2.1.63, almond emulzin fukozidaza, alfa-(1->2)-L-fukozidaza) je enzim sa sistematskim imenom 2-alfa-L-fukopiranozil-beta-D-galaktozid fukohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- metil-2-alfa-L-fukopiranozil-beta-D-galaktozid + H2O L-fukoza + metil beta-D-galaktozid
Ovaj enzim je visoko specifičan za neredukujuće terminalne L-fukozne ostatake vezane za D-galaktozne ostatke 1,2-alfa-vezom.
Reference
- ↑ Bahl, O.P. (1970). „Glycosidases of Aspergillus niger. II. Purification and general properties of 1,2-α-L-fucosidase”. J. Biol. Chem. 245: 299-304. PMID 5460888.
- ↑ Ogata-Arakawa, M., Muramatsu, T. and Kobata, A. (1977). „α-L-Fucosidases from almond emulsin: characterization of the two enzymes with different specificities”. Arch. Biochem. Biophys. 181: 353-358. PMID 18111.
- ↑ Reglero, A. and Cabezas, J.A. (1976). „Glycosidases of molluscs. Purification and properties of α-L-fucosidase from Chamelea gallina L”. Eur. J. Biochem. 66: 379-387. PMID 7458.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH 1,2-alpha-L-fucosidase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
