CDKN1B |
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PDBに登録されている構造 |
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PDB | オルソログ検索: RCSB PDBe PDBj |
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PDBのIDコード一覧 |
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2AST, 1H27, 1JSU |
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識別子 |
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記号 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1, cyclin-dependent kinase inhibitor 1B, cyclin dependent kinase inhibitor 1B |
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外部ID | OMIM: 600778 MGI: 104565 HomoloGene: 2999 GeneCards: CDKN1B |
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遺伝子オントロジー |
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分子機能 | • 血漿タンパク結合 • protein phosphatase binding • cyclin-dependent protein serine/threonine kinase activity • protein kinase inhibitor activity • プロテインキナーゼ結合 • cyclin binding • cyclin-dependent protein serine/threonine kinase inhibitor activity • Hsp70タンパク質結合 • protein-containing complex binding • シャペロン結合
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細胞の構成要素 | • 細胞質 • 細胞質基質 • エンドソーム • 核質 • Cul4A-RING E3 ubiquitin ligase complex • 細胞核 • intracellular membrane-bounded organelle • 高分子複合体
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生物学的プロセス | • Notchシグナリング • regulation of cyclin-dependent protein serine/threonine kinase activity • DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest • エストラジオールへの反応 • positive regulation of cell death • 低酸素症への反応 • response to amino acid • response to cadmium ion • positive regulation of protein catabolic process • 有機環状化合物への反応 • cellular response to lithium ion • cellular response to organic cyclic compound • response to peptide hormone • 細胞死 • negative regulation of apoptotic process • 聴覚 • response to glucose • potassium ion transport • regulation of cell population proliferation • negative regulation of cell growth • negative regulation of epithelial cell proliferation involved in prostate gland development • positive regulation of cell population proliferation • positive regulation of cyclin-dependent protein serine/threonine kinase activity • negative regulation of epithelial cell proliferation • positive regulation of microtubule polymerization • inner ear development • cellular response to antibiotic • 細胞周期 • negative regulation of phosphorylation • negative regulation of transcription, DNA-templated • autophagic cell death • negative regulation of cell population proliferation • negative regulation of mitotic cell cycle • negative regulation of kinase activity • positive regulation of cell cycle • negative regulation of vascular associated smooth muscle cell proliferation • 胎座 • regulation of exit from mitosis • regulation of lens fiber cell differentiation • negative regulation of cyclin-dependent protein kinase activity • negative regulation of cell cycle • negative regulation of cyclin-dependent protein serine/threonine kinase activity • G1/S transition of mitotic cell cycle
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出典:Amigo / QuickGO |
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オルソログ |
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種 | ヒト | マウス |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (タンパク質) | | |
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場所 (UCSC) | Chr 12: 12.69 – 12.72 Mb | Chr 12: 134.9 – 134.9 Mb |
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PubMed検索 | [3] | [4] |
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ウィキデータ |
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