エンド-α-シアリダーゼ |
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識別子 |
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EC番号 | 3.2.1.129 |
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CAS登録番号 | 91195-87-8 |
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データベース |
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IntEnz | IntEnz view |
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BRENDA | BRENDA entry |
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ExPASy | NiceZyme view |
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KEGG | KEGG entry |
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MetaCyc | metabolic pathway |
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PRIAM | profile |
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PDB構造 | RCSB PDB PDBj PDBe PDBsum |
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テンプレートを表示 |
エンド-α-シアリダーゼ(Endo-alpha-sialidase、EC 3.2.1.129)は、系統名をポリシアロシド (2->8)-α-シアロシルヒドロラーゼ (polysialoside (2->8)-alpha-sialosylhydrolase)という酵素である[1][2][3][4][5][6][7]。他に、endo-N-acylneuraminidase, endoneuraminidase, endo-N-acetylneuraminidase, poly(alpha-2,8-sialosyl) endo-N-acetylneuraminidase, poly(alpha-2,8-sialoside) alpha-2,8-sialosylhydrolase, endosialidase, endo-N等とも呼ばれる。以下の化学反応を触媒する。
- オリゴまたはポリシアル酸の(2->8)-α-シアロシル結合をエンド型で加水分解する。
出典
- ^ “Cleavage of the polysialosyl units of brain glycoproteins by a bacteriophage endosialidase. Involvement of a long oligosaccharide segment in molecular interactions of polysialic acid”. The Journal of Biological Chemistry 260 (2): 1265–70. (January 1985). PMID 3968060.
- ^ “Purification and properties of a bacteriophage-induced endo-N-acetylneuraminidase specific for poly-alpha-2,8-sialosyl carbohydrate units”. The Journal of Biological Chemistry 262 (8): 3553–61. (March 1987). PMID 3546309.
- ^ “Use of a bacteriophage-derived endo-N-acetylneuraminidase and an equine antipolysialyl antibody to characterize the polysialyl residues in salmonid fish egg polysialoglycoproteins. Substrate and immunospecificity studies”. The Journal of Biological Chemistry 263 (34): 18269–76. (December 1988). PMID 3142874.
- ^ “Endo-N-acetylneuraminidase associated with bacteriophage particles”. Journal of Virology 43 (2): 697–704. (August 1982). PMC 256172. PMID 7109038. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC256172/.
- ^ “Common cleavage pattern of polysialic acid by bacteriophage endosialidases of different properties and origins”. Journal of Virology 63 (10): 4409–16. (October 1989). PMC 251059. PMID 2778882. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC251059/.
- ^ “Neuraminidase associated with coliphage E that specifically depolymerizes the Escherichia coli K1 capsular polysaccharide”. Journal of Virology 55 (2): 374–8. (August 1985). PMC 254943. PMID 3894684. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC254943/.
- ^ “Some questions and suggestions on the type references of the official nomenclature (IUB) for sialidase(s) and endosialidase”. The Biochemical Journal 278 ( Pt 1): 311–2. (August 1991). doi:10.1042/bj2780311. PMC 1151486. PMID 1883340. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1151486/.
外部リンク