MYOD1 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/6/61/Protein_MYOD1_PDB_1mdy.png/250px-Protein_MYOD1_PDB_1mdy.png) |
Structure de la protéine MYOD1. Basé sur l'identifiant PDB 1mdy. |
Structures disponibles |
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PDB | Recherche d'orthologue: PDBe RCSB |
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Identifiants |
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Aliases | MYOD1 |
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IDs externes | OMIM: 159970 MGI: 97275 HomoloGene: 7857 GeneCards: MYOD1 |
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Position du gène (Homme) |
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![Chromosome 11 humain](//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_human_chromosome_11.svg/300px-Ideogram_human_chromosome_11.svg.png) | Chr. | Chromosome 11 humain[1] |
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| Locus | 11p15.1 | Début | 17,719,571 bp[1] |
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Fin | 17,722,136 bp[1] |
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Position du gène (Souris) |
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![Chromosome 7 (souris)](//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/260px-Ideogram_house_mouse_chromosome_7.svg.png) | Chr. | Chromosome 7 (souris)[2] |
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| Locus | 7 B3|7 30.03 cM | Début | 46,025,898 bp[2] |
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Fin | 46,028,523 bp[2] |
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Expression génétique |
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Bgee | Humain | Souris (orthologue) |
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Fortement exprimé dans | - muscle triceps brachial
- Skeletal muscle tissue of biceps brachii
- muscle glutéal
- muscle vaste latéral
- Skeletal muscle tissue of rectus abdominis
- muscle de la cuisse
- muscle gastrocnémien
- testicule
- muscle deltoïde
- gonade
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| Fortement exprimé dans | - Myotome
- poignet
- muscles de la langue
- muscle de la cuisse
- muscle triceps brachial
- muscle sterno-cléido-mastoïdien
- muscle temporal
- skeletal muscle tissue
- articulation du genou
- muscle long extenseur des orteils
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| Plus de données d'expression de référence |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/2/2a/PBB_GE_MYOD1_206657_s_at_fs.png/250px-PBB_GE_MYOD1_206657_s_at_fs.png) | Plus de données d'expression de référence |
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Gene Ontology |
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Fonction moléculaire | - liaison ADN
- sequence-specific DNA binding
- RNA polymerase II transcription regulatory region sequence-specific DNA binding
- protein dimerization activity
- DNA-binding transcription activator activity, RNA polymerase II-specific
- DNA-binding transcription factor activity
- transcription factor binding
- liaison de chromatine
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
- E-box binding
- liaison protéique
- protein heterodimerization activity
- liaison enzymatique
- transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
- chromatin DNA binding
- ubiquitin protein ligase binding
- transcription coactivator activity
- DNA-binding transcription factor activity, RNA polymerase II-specific
- promoter-specific chromatin binding
| Composant cellulaire | - transcription regulator complex
- nucléoplasme
- myofibrille
- noyau
- cytoplasme
- cytosol
- corps nucléaire
| Processus biologique | - différenciation cellulaire
- myotube differentiation
- regulation of transcription, DNA-templated
- regulation of transcription by RNA polymerase II
- cellular response to starvation
- muscle cell fate commitment
- cellular response to estradiol stimulus
- skeletal muscle fiber adaptation
- muscle organ development
- regulation of alternative mRNA splicing, via spliceosome
- myotube cell development
- positive regulation of skeletal muscle fiber development
- negative regulation of myoblast proliferation
- transcription, DNA-templated
- développent d'un organisme multicellulaire
- régulation positive de la transcription dépendante de l'ADN
- phosphorylation des protéines
- regulation of RNA splicing
- positive regulation of myoblast fusion
- myoblast fate determination
- cellular response to glucocorticoid stimulus
- positive regulation of myoblast differentiation
- skeletal muscle fiber development
- histone H3 acetylation
- myotube differentiation involved in skeletal muscle regeneration
- histone H4 acetylation
- skeletal muscle cell differentiation
- positive regulation of skeletal muscle tissue regeneration
- régulation de l'expression des gènes
- striated muscle cell differentiation
- cellular response to oxygen levels
- myoblast fusion
- myoblast differentiation
- skeletal muscle tissue development
- positive regulation of transcription by RNA polymerase II
- transcription by RNA polymerase II
- positive regulation of muscle cell differentiation
- cellular response to tumor necrosis factor
- positive regulation of snRNA transcription by RNA polymerase II
| Sources:Amigo / QuickGO |
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Orthologues |
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Espèces | Homme | Souris |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protéine) | | |
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Localisation (UCSC) | Chr 11: 17.72 – 17.72 Mb | Chr 7: 46.03 – 46.03 Mb |
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Publication PubMed | [3] | [4] |
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Wikidata |
Voir/Editer Humain | Voir/Editer Souris |
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