ZDHHC3

Protein-coding gene in the species Homo sapiens
ZDHHC3
Identifiers
AliasesZDHHC3, DHHC-3, GODZ, ZNF373, zinc finger DHHC-type containing 3, DHHC3, zinc finger DHHC-type palmitoyltransferase 3
External IDsOMIM: 617150; MGI: 1926134; HomoloGene: 9582; GeneCards: ZDHHC3; OMA:ZDHHC3 - orthologs
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for ZDHHC3
Genomic location for ZDHHC3
Band3p21.31Start44,915,257 bp[1]
End44,976,185 bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for ZDHHC3
Genomic location for ZDHHC3
Band9|9 F4Start123,066,160 bp[2]
End123,113,205 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • left testis

  • right testis

  • rectum

  • stromal cell of endometrium

  • skin of leg

  • left adrenal gland

  • right adrenal gland

  • sperm

  • skin of abdomen

  • left adrenal cortex
Top expressed in
  • granulocyte

  • muscle of thigh

  • lip

  • tail of embryo

  • genital tubercle

  • pontine nuclei

  • left lung

  • epiblast

  • dorsal tegmental nucleus

  • yolk sac
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • protein-cysteine S-palmitoyltransferase activity
  • palmitoyltransferase activity
  • transferase activity
  • acyltransferase activity
Cellular component
  • integral component of membrane
  • Golgi membrane
  • Golgi apparatus
  • membrane
  • endoplasmic reticulum
Biological process
  • protein targeting
  • protein palmitoylation
  • protein targeting to membrane
  • peptidyl-L-cysteine S-palmitoylation
  • localization within membrane
  • protein localization to photoreceptor outer segment
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

51304

69035

Ensembl

ENSG00000163812

ENSMUSG00000025786

UniProt

Q9NYG2

Q8R173

RefSeq (mRNA)
NM_001135179
NM_001135180
NM_016598
NM_001330761
NM_001349376

NM_001349377
NM_001349378
NM_001349379
NM_001349380
NM_001349381

NM_026917

RefSeq (protein)
NP_001128651
NP_001317690
NP_057682
NP_001336305
NP_001336306

NP_001336307
NP_001336308
NP_001336309
NP_001336310

NP_081193
NP_001359467
NP_001359468
NP_001359469
NP_001359470

NP_001359471
NP_001359472
NP_001359473
NP_001359475
NP_001359476
NP_001359477
NP_001359478
NP_001359479
NP_001359480
NP_001359481
NP_001359482

Location (UCSC)Chr 3: 44.92 – 44.98 MbChr 9: 123.07 – 123.11 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Palmitoyltransferase ZDHHC3 is an enzyme that in humans is encoded by the ZDHHC3 gene that contains a DHHC domain.[5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163812 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025786 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: ZDHHC3 zinc finger, DHHC-type containing 3".

Further reading

  • Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Uemura T, Mori H, Mishina M (2002). "Isolation and characterization of Golgi apparatus-specific GODZ with the DHHC zinc finger domain". Biochem. Biophys. Res. Commun. 296 (2): 492–6. doi:10.1016/S0006-291X(02)00900-2. PMID 12163046.
  • Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
  • Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.


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