TXNDC9

Protein-coding gene in the species Homo sapiens
TXNDC9
Identifiers
AliasesTXNDC9, APACD, PHLP3, thioredoxin domain containing 9
External IDsOMIM: 612564; MGI: 2138153; HomoloGene: 4225; GeneCards: TXNDC9; OMA:TXNDC9 - orthologs
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for TXNDC9
Genomic location for TXNDC9
Band2q11.2Start99,318,982 bp[1]
End99,340,702 bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for TXNDC9
Genomic location for TXNDC9
Band1|1 BStart38,024,270 bp[2]
End38,036,974 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • oocyte

  • epithelium of nasopharynx

  • hair follicle

  • endothelial cell

  • secondary oocyte

  • gonad

  • oral cavity

  • skin of hip

  • islet of Langerhans

  • right ventricle
Top expressed in
  • blastocyst

  • morula

  • zygote

  • ventricular zone

  • esophagus

  • intestinal villus

  • Ileal epithelium

  • spermatid

  • tail of embryo

  • embryo
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • protein binding
  • queuine tRNA-ribosyltransferase activity
  • cadherin binding
Cellular component
  • cytoplasm
  • centrosome
  • midbody
  • cytoskeleton
  • nucleus
  • microtubule organizing center
  • cellular component
  • cytosol
Biological process
  • queuosine biosynthetic process
  • cell redox homeostasis
  • biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

10190

98258

Ensembl

ENSG00000115514

ENSMUSG00000058407

UniProt

O14530

Q9CQ79

RefSeq (mRNA)

NM_005783

NM_172054

RefSeq (protein)

NP_005774

NP_742051

Location (UCSC)Chr 2: 99.32 – 99.34 MbChr 1: 38.02 – 38.04 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Thioredoxin domain-containing protein 9 is a protein that in humans is encoded by the TXNDC9 gene.[5][6]

The protein encoded by this gene is a member of the thioredoxin family. The exact function of this protein is not known but it is associated with cell differentiation.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000115514 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000058407 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  6. ^ a b "Entrez Gene: TXNDC9 thioredoxin domain containing 9".

Further reading

  • Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923.
  • Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi:10.1038/nature03466. PMID 15815621.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ogawa S, Matsubayashi Y, Nishida E (2004). "An evolutionarily conserved gene required for proper microtubule architecture in Caenorhabditis elegans". Genes Cells. 9 (2): 83–93. doi:10.1111/j.1356-9597.2004.00708.x. PMID 15009089. S2CID 23313088.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
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TXNDC human genes


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