TMEM150

Protein-coding gene in the species Homo sapiens
TMEM150A
Identifiers
AliasesTMEM150A, TM6P1, TMEM150, transmembrane protein 150A, TTN1
External IDsOMIM: 616757; MGI: 2385244; HomoloGene: 16378; GeneCards: TMEM150A; OMA:TMEM150A - orthologs
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for TMEM150A
Genomic location for TMEM150A
Band2p11.2Start85,598,547 bp[1]
End85,603,196 bp[1]
Gene location (Mouse)
Chromosome 6 (mouse)
Chr.Chromosome 6 (mouse)[2]
Chromosome 6 (mouse)
Genomic location for TMEM150A
Genomic location for TMEM150A
Band6|6 C1Start72,332,430 bp[2]
End72,336,745 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • body of pancreas

  • gastrocnemius muscle

  • right lobe of liver

  • muscle of thigh

  • right testis

  • left testis

  • upper lobe of left lung

  • body of stomach

  • gastric mucosa

  • anterior pituitary
Top expressed in
  • yolk sac

  • renal cortex

  • proximal tubule

  • placenta

  • right kidney

  • human kidney

  • liver

  • secondary oocyte

  • skeletal muscle tissue

  • muscle of thigh
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein binding
Cellular component
  • integral component of membrane
  • plasma membrane
  • lysosome
  • integral component of plasma membrane
  • membrane
Biological process
  • phosphatidylinositol phosphate biosynthetic process
  • catabolic process
  • protein localization to plasma membrane
  • regulation of autophagy
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

129303

232086

Ensembl

ENSG00000168890

ENSMUSG00000055912

UniProt

Q86TG1

Q91WN2

RefSeq (mRNA)

NM_001031738
NM_153342
NM_001369917

NM_144916

RefSeq (protein)

NP_001026908
NP_699173
NP_001356846

NP_659165

Location (UCSC)Chr 2: 85.6 – 85.6 MbChr 6: 72.33 – 72.34 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transmembrane protein 150A is a protein that, in humans, is encoded by the TMEM150A gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000168890 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000055912 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Zhang J, D'Ercole AJ, Underwood LE (Sep 2000). "Identification of a new gene (rat TM6P1) encoding a fasting-inducible, integral membrane protein with six transmembrane domains". Biochim Biophys Acta. 1492 (1): 280–4. doi:10.1016/s0167-4781(00)00104-4. PMID 10858565.
  6. ^ "Entrez Gene: TMEM150 transmembrane protein 150".

Further reading

  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi:10.1038/nature03466. PMID 15815621.
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.


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