TLE4 |
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Identifiers |
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Aliases | TLE4, BCE-1, BCE1, E(spI), ESG, ESG4, GRG4, Grg-4, transducin like enhancer of split 4, TLE family member 4, transcriptional corepressor, E(spl) |
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External IDs | OMIM: 605132; MGI: 104633; HomoloGene: 38259; GeneCards: TLE4; OMA:TLE4 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 9 (human)[1] |
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| Band | 9q21.31 | Start | 79,571,773 bp[1] |
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End | 79,726,882 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 19 (mouse)[2] |
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| Band | 19 A|19 9.11 cM | Start | 14,425,514 bp[2] |
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End | 14,575,415 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - optic nerve
- left testis
- right testis
- endothelial cell
- corpus callosum
- inferior olivary nucleus
- inferior ganglion of vagus nerve
- dorsal motor nucleus of vagus nerve
- Region I of hippocampus proper
- bone marrow cells
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| Top expressed in | - renal corpuscle
- medullary collecting duct
- vestibular membrane of cochlear duct
- superior cervical ganglion
- suprachiasmatic nucleus
- conjunctival fornix
- nucleus accumbens
- retinal pigment epithelium
- tail of embryo
- olfactory tubercle
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
- chromatin binding
- protein binding
- transcription corepressor activity
- DNA-binding transcription factor activity, RNA polymerase II-specific
- molecular function
| Cellular component | - nucleus
- nucleoplasm
- transcription regulator complex
- beta-catenin-TCF complex
| Biological process | - negative regulation of transcription, DNA-templated
- regulation of transcription, DNA-templated
- negative regulation of transcription by RNA polymerase II
- Wnt signaling pathway
- transcription, DNA-templated
- beta-catenin-TCF complex assembly
- cellular response to leukemia inhibitory factor
- biological process
- negative regulation of canonical Wnt signaling pathway
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001282748 NM_001282749 NM_001282753 NM_001282760 NM_007005
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NM_001351541 NM_001351542 NM_001351543 NM_001351546 NM_001351547 NM_001351550 NM_001351552 NM_001351558 NM_001351560 NM_001351562 NM_001351563 NM_001351564 NM_001351556 |
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NM_011600 NM_001302947 NM_001302950 NM_001302951 |
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RefSeq (protein) | NP_001269677 NP_001269678 NP_001269682 NP_001269689 NP_008936
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NP_001338470 NP_001338471 NP_001338472 NP_001338475 NP_001338476 NP_001338479 NP_001338481 NP_001338487 NP_001338489 NP_001338491 NP_001338492 NP_001338493 NP_001338485 |
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NP_001289876 NP_001289879 NP_001289880 NP_035730 |
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Location (UCSC) | Chr 9: 79.57 – 79.73 Mb | Chr 19: 14.43 – 14.58 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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