Sclerotiorin
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Preferred IUPAC name (7R)-5-Chloro-3-[(1E,3E,5S)-3,5-dimethylhepta-1,3-dien-1-yl]-6,8-dioxo-7,8-dihydro-6H-2-benzopyran-7-yl acetate | |
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Chemical formula | C21H23ClO5 |
Molar mass | 390.86 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
Sclerotiorin is an antimicrobial Penicillium frequentans isolate. Sclerotiorin is an aldose reductase inhibitor (IC50=0.4 μM) as well as a reversible lipoxygenase inhibitor (IC50=4.2 μM).[1][2]
Notes
- ^ Chidananda, C; Rao, LJ; Sattur, AP (2006). "Sclerotiorin, from Penicillium frequentans, a potent inhibitor of aldose reductase". Biotechnology Letters. 28 (20): 1633–6. doi:10.1007/s10529-006-9133-4. PMID 16900332. S2CID 29703251.
- ^ Chidananda C, Sattur AP (2007). "Sclerotiorin, a novel inhibitor of lipoxygenase from Penicillium frequentans". J Agric Food Chem. 55 (8): 2879–83. doi:10.1021/jf062032x. PMID 17385879.
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