PIK3R4 |
---|
|
Identifiers |
---|
Aliases | PIK3R4, VPS15, p150, phosphoinositide-3-kinase regulatory subunit 4 |
---|
External IDs | OMIM: 602610; MGI: 1922919; HomoloGene: 24678; GeneCards: PIK3R4; OMA:PIK3R4 - orthologs |
---|
Gene location (Human) |
---|
| Chr. | Chromosome 3 (human)[1] |
---|
| Band | 3q22.1 | Start | 130,678,934 bp[1] |
---|
End | 130,746,829 bp[1] |
---|
|
Gene location (Mouse) |
---|
| Chr. | Chromosome 9 (mouse)[2] |
---|
| Band | 9 F1|9 56.79 cM | Start | 105,520,177 bp[2] |
---|
End | 105,564,856 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - right lobe of liver
- gonad
- anterior pituitary
- epithelium of colon
- right lobe of thyroid gland
- Brodmann area 9
- epithelium of nasopharynx
- ventricular zone
- mucosa of transverse colon
- left lobe of thyroid gland
|
| Top expressed in | - primary oocyte
- secondary oocyte
- zygote
- Epithelium of choroid plexus
- otic vesicle
- motor neuron
- medullary collecting duct
- iris
- facial motor nucleus
- tail of embryo
|
| More reference expression data |
|
---|
BioGPS | |
---|
|
Gene ontology |
---|
Molecular function | - transferase activity
- protein kinase activity
- nucleotide binding
- kinase activity
- protein serine/threonine kinase activity
- protein binding
- ATP binding
- 1-phosphatidylinositol-3-kinase activity
| Cellular component | - cytosol
- endosome
- late endosome
- phagocytic vesicle membrane
- membrane
- phosphatidylinositol 3-kinase complex, class III
- nuclear pore
- autophagosome
- phosphatidylinositol 3-kinase complex, class III, type I
- axoneme
- nucleus-vacuole junction
- cytoplasmic vesicle
- phosphatidylinositol 3-kinase complex, class III, type II
- microtubule cytoskeleton
- intracellular membrane-bounded organelle
| Biological process | - cellular response to glucose starvation
- regulation of cytokinesis
- phosphorylation
- late endosome to vacuole transport
- autophagy of peroxisome
- receptor catabolic process
- positive regulation of phosphatidylinositol 3-kinase activity
- protein phosphorylation
- phosphatidylinositol biosynthetic process
- protein targeting to vacuole
- toll-like receptor 9 signaling pathway
- macroautophagy
- phosphatidylinositol-3-phosphate biosynthetic process
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | | |
---|
RefSeq (protein) | | |
---|
Location (UCSC) | Chr 3: 130.68 – 130.75 Mb | Chr 9: 105.52 – 105.56 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|