PHTF2

Protein-coding gene in the species Homo sapiens
PHTF2
Identifiers
AliasesPHTF2, putative homeodomain transcription factor 2
External IDsOMIM: 616785; MGI: 1916020; HomoloGene: 10713; GeneCards: PHTF2; OMA:PHTF2 - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for PHTF2
Genomic location for PHTF2
Band7q11.23-q21.11Start77,798,773 bp[1]
End77,957,503 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for PHTF2
Genomic location for PHTF2
Band5|5 A3Start20,758,663 bp[2]
End20,882,124 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • tibia

  • Skeletal muscle tissue of rectus abdominis

  • biceps brachii

  • Skeletal muscle tissue of biceps brachii

  • triceps brachii muscle

  • glutes

  • thoracic diaphragm

  • amniotic fluid

  • vastus lateralis muscle

  • deltoid muscle
Top expressed in
  • plantaris muscle

  • extensor digitorum longus muscle

  • cardiac muscle tissue of left ventricle

  • secondary oocyte

  • muscle of thigh

  • soleus muscle

  • quadriceps femoris muscle

  • zygote

  • sternocleidomastoid muscle

  • primary oocyte
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • DNA binding
Cellular component
  • endoplasmic reticulum
  • nucleus
Biological process
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

57157

68770

Ensembl

ENSG00000006576

ENSMUSG00000039987

UniProt

Q8N3S3

Q8CB19

RefSeq (mRNA)
NM_001127357
NM_001127358
NM_001127359
NM_001127360
NM_020432

NM_001366081
NM_001366082
NM_001366083
NM_001366084
NM_001366085
NM_001366086
NM_001366087
NM_001366088
NM_001366089
NM_001395270
NM_001395271
NM_001395272

NM_172992

RefSeq (protein)
NP_001120829
NP_001120830
NP_001120831
NP_001120832
NP_065165

NP_001353010
NP_001353011
NP_001353012
NP_001353013
NP_001353014
NP_001353015
NP_001353016
NP_001353017
NP_001353018

NP_766580

Location (UCSC)Chr 7: 77.8 – 77.96 MbChr 5: 20.76 – 20.88 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Putative homeodomain transcription factor 2 is a protein that in humans is encoded by the PHTF2 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000006576 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039987 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Manuel A, Beaupain D, Romeo PH, Raich N (May 2000). "Molecular characterization of a novel gene family (PHTF) conserved from Drosophila to mammals". Genomics. 64 (2): 216–20. doi:10.1006/geno.1999.6079. PMID 10729229.
  6. ^ "Entrez Gene: PHTF2 putative homeodomain transcription factor 2".

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.


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