NHLRC1 |
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Identifiers |
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Aliases | NHLRC1, EPM2A, EPM2B, MALIN, bA204B7.2, NHL repeat containing E3 ubiquitin protein ligase 1 |
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External IDs | OMIM: 608072; MGI: 2145264; HomoloGene: 18439; GeneCards: NHLRC1; OMA:NHLRC1 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 6 (human)[1] |
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| Band | 6p22.3 | Start | 18,120,440 bp[1] |
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End | 18,122,677 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 13 (mouse)[2] |
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| Band | 13|13 A5 | Start | 47,166,033 bp[2] |
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End | 47,168,326 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - prefrontal cortex
- islet of Langerhans
- muscle of thigh
- right lobe of liver
- superior frontal gyrus
- stromal cell of endometrium
- gastrocnemius muscle
- Brodmann area 9
- skin of leg
- right adrenal gland
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| Top expressed in | - interventricular septum
- dorsomedial hypothalamic nucleus
- arcuate nucleus
- median eminence
- paraventricular nucleus of hypothalamus
- ventromedial nucleus
- ventral tegmental area
- suprachiasmatic nucleus
- habenula
- subiculum
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - metal ion binding
- protein binding
- ubiquitin protein ligase activity
- ubiquitin-protein transferase activity
- transferase activity
| Cellular component | - perinuclear region of cytoplasm
- cytosol
- endoplasmic reticulum
- nucleus
| Biological process | - autophagy
- protein polyubiquitination
- glycogen biosynthetic process
- positive regulation of protein ubiquitination
- protein ubiquitination
- proteasome-mediated ubiquitin-dependent protein catabolic process
- regulation of protein phosphorylation
- glycogen metabolic process
- regulation of gene expression
- regulation of protein ubiquitination
- response to endoplasmic reticulum stress
- cellular macromolecule metabolic process
- regulation of protein kinase activity
- regulation of protein localization to plasma membrane
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 6: 18.12 – 18.12 Mb | Chr 13: 47.17 – 47.17 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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