N-acylneuraminate-9-phosphatase
N-acylneuraminate-9-phosphatase | |||||||||
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N-acylneuraminate-9-phosphatase homodimer, Human | |||||||||
Identifiers | |||||||||
EC no. | 3.1.3.29 | ||||||||
CAS no. | 37288-13-4 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme N-acylneuraminate-9-phosphatase (EC 3.1.3.29) catalyzes the reaction
- N-acylneuraminate 9-phosphate + H2O N-acylneuraminate + phosphate
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is N-acylneuraminate-9-phosphate phosphohydrolase. Other names in common use include acylneuraminate 9-phosphatase, N-acylneuraminic acid 9-phosphate phosphatase, and N-acylneuraminic (sialic) acid 9-phosphatase. This enzyme participates in aminosugars metabolism.
References
- Jourdian GW, Swanson A, Watson D, Roseman S (1966). "N-acylneuraminic (Sialic) acid 9-phosphatase". N-Acetylneuraminic (sialic) acid 9-phosphatase. Methods Enzymol. Vol. 8. pp. 205–208. doi:10.1016/0076-6879(66)08034-0. ISBN 978-0-12-181808-1.
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Hydrolase: esterases (EC 3.1)
ester hydrolases
- Alkaline phosphatase
- Acid phosphatase (Prostatic)/Tartrate-resistant acid phosphatase/Purple acid phosphatases
- Nucleotidase
- Glucose 6-phosphatase
- Fructose 1,6-bisphosphatase
- Protein phosphatase
- OCRL
- Pyruvate dehydrogenase phosphatase
- Fructose 6-P,2-kinase:fructose 2,6-bisphosphatase
- PTEN
- Phytase
- Inositol-phosphate phosphatase
- Protein phosphatase: Protein tyrosine phosphatase
- Protein serine/threonine phosphatase
- Dual-specificity phosphatase
Phosphodiesterase
deoxyribonuclease
and ribonuclease)
3.1.11-16: Exonuclease |
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3.1.21-31: Endonuclease |
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