HEPBS
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Names | |
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Preferred IUPAC name 4-[4-(2-Hydroxyethyl)piperazin-1-yl]butane-1-sulfonic acid | |
Other names HEPBS | |
Identifiers | |
CAS Number |
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3D model (JSmol) |
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ECHA InfoCard | 100.157.294 ![]() |
PubChem CID |
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CompTox Dashboard (EPA) |
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InChI
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Properties | |
Chemical formula | C10H22N2O4S |
Molar mass | 266.356 g/mol |
Appearance | White crystalline powder |
Density | 1.25 g/cm3 (predicted) |
Melting point | 211–216 °C (412–421 °F; 484–489 K) |
Acidity (pKa) | 8.3 |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards | Irritant |
GHS labelling: | |
Warning | |
Hazard statements | H315, H319, H335 |
Precautionary statements | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501 |
Flash point | Non-flammable |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
HEPBS (N-(2-Hydroxyethyl)piperazine-N'-(4-butanesulfonic acid)) is a zwitterionic organic chemical buffering agent; one of Good's buffers. HEPBS and HEPES have very similar structures and properties, HEPBS also having an acidity (pKa) in the physiological range (7.6-9.0 useful range). This makes it possible to use it for cell culture work.
![](http://upload.wikimedia.org/wikipedia/commons/thumb/6/66/HEPBS_1H_NMR_spectrum.png/220px-HEPBS_1H_NMR_spectrum.png)