FZD5 |
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Identifiers |
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Aliases | FZD5, C2orf31, HFZ5, frizzled class receptor 5 |
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External IDs | OMIM: 601723; MGI: 108571; HomoloGene: 2590; GeneCards: FZD5; OMA:FZD5 - orthologs |
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Gene location (Human) |
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![Chromosome 2 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Ideogram_human_chromosome_2.svg/300px-Ideogram_human_chromosome_2.svg.png) | Chr. | Chromosome 2 (human)[1] |
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| Band | 2q33.3 | Start | 207,762,598 bp[1] |
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End | 207,769,906 bp[1] |
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Gene location (Mouse) |
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![Chromosome 1 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Ideogram_house_mouse_chromosome_1.svg/260px-Ideogram_house_mouse_chromosome_1.svg.png) | Chr. | Chromosome 1 (mouse)[2] |
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| Band | 1 C2|1 32.74 cM | Start | 64,769,717 bp[2] |
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End | 64,776,910 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - jejunal mucosa
- mucosa of sigmoid colon
- lower lobe of lung
- mucosa of ileum
- duodenum
- mucosa of transverse colon
- palpebral conjunctiva
- kidney tubule
- visceral pleura
- tibia
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| Top expressed in | - median eminence
- hair follicle
- epithelium of small intestine
- epithelium of stomach
- ciliary body
- left colon
- arcuate nucleus
- Paneth cell
- calvaria
- ileum
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/8/80/PBB_GE_FZD5_206136_at_fs.png/250px-PBB_GE_FZD5_206136_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - amyloid-beta binding
- signal transducer activity
- Wnt-protein binding
- protein binding
- protein kinase binding
- ubiquitin protein ligase binding
- transmembrane signaling receptor activity
- Wnt-activated receptor activity
- G protein-coupled receptor activity
| Cellular component | - clathrin-coated endocytic vesicle membrane
- Golgi apparatus
- early endosome membrane
- membrane
- bicellular tight junction
- Golgi membrane
- plasma membrane
- cell surface
- early endosome
- perinuclear region of cytoplasm
- integral component of membrane
| Biological process | - G protein-coupled receptor signaling pathway
- T cell differentiation in thymus
- chorionic trophoblast cell differentiation
- positive regulation of protein targeting to mitochondrion
- positive regulation of JUN kinase activity
- apoptotic process involved in morphogenesis
- regulation of chorionic trophoblast cell proliferation
- regulation of bicellular tight junction assembly
- regulation of canonical Wnt signaling pathway
- cellular response to molecule of bacterial origin
- positive regulation of interferon-gamma production
- embryonic axis specification
- labyrinthine layer blood vessel development
- cell maturation
- Wnt signaling pathway
- embryonic camera-type eye development
- multicellular organism development
- cell surface receptor signaling pathway
- vasculature development
- regulation of autophagy of mitochondrion
- branching involved in labyrinthine layer morphogenesis
- embryonic camera-type eye morphogenesis
- post-embryonic camera-type eye development
- positive regulation of T cell cytokine production
- angiogenesis
- neuron differentiation
- Wnt signaling pathway involved in dorsal/ventral axis specification
- canonical Wnt signaling pathway
- synapse assembly
- syncytiotrophoblast cell differentiation involved in labyrinthine layer development
- anterior/posterior axis specification, embryo
- Spemann organizer formation
- positive regulation of transcription by RNA polymerase II
- negative regulation of cell population proliferation
- signal transduction
- Wnt signaling pathway, calcium modulating pathway
- Wnt signaling pathway, planar cell polarity pathway
- beta-catenin destruction complex disassembly
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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NM_001033193 NM_001042659 NM_022721 |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 2: 207.76 – 207.77 Mb | Chr 1: 64.77 – 64.78 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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