ABI3BP

Protein-coding gene in the species Homo sapiens

ABI3BP

Identifiers

Aliases

ABI3BP, NESHBP, TARSH, ABI family member 3 binding protein

External IDs

OMIM: 606279; HomoloGene: 137312; GeneCards: ABI3BP; OMA:ABI3BP - orthologs

Gene location (Human)

Chr.	Chromosome 3 (human)^[1]

Band	3q12.2	Start	100,749,156 bp^[1]
Band	3q12.2	End	100,993,515 bp^[1]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

decidua

synovial joint

Achilles tendon

vena cava

skin of hip

epithelium of colon

saphenous vein

superficial temporal artery

parietal pleura

urethra

n/a

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	glycosaminoglycan binding heparin binding collagen binding extracellular matrix structural constituent
Cellular component	extracellular matrix interstitial matrix extracellular space extracellular region collagen-containing extracellular matrix
Biological process	extracellular matrix organization positive regulation of cell-substrate adhesion
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


25890


n/a

Ensembl


ENSG00000154175


n/a

UniProt


Q7Z7G0


n/a

RefSeq (mRNA)

NM_015429 NM_001349329 NM_001349330 NM_001349331 NM_001349332
NM_001365642 NM_001365643 NM_001375547 NM_001375549 NM_001375550 NM_001377332


n/a

RefSeq (protein)

NP_056244 NP_001336258 NP_001336259 NP_001336260 NP_001336261
NP_001352571 NP_001352572 NP_001362476 NP_001362478 NP_001362479 NP_001364261


n/a

Location (UCSC)

Chr 3: 100.75 – 100.99 Mb

n/a

PubMed search

^[2]

n/a

Wikidata

View/Edit Human

ABI family member 3 binding protein is a protein that in humans is encoded by the ABI3BP gene. ^[3]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000154175 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: ABI family member 3 binding protein". Retrieved 2017-09-13.

Uekawa N, Terauchi K, Nishikimi A, Shimada J, Maruyama M (2005). "Expression of TARSH gene in MEFs senescence and its potential implication in human lung cancer". Biochem. Biophys. Res. Commun. 329 (3): 1031–8. doi:10.1016/j.bbrc.2005.02.068. PMID 15752759.
Terauchi K, Shimada J, Uekawa N, Yaoi T, Maruyama M, Fushiki S (2006). "Cancer-associated loss of TARSH gene expression in human primary lung cancer". J. Cancer Res. Clin. Oncol. 132 (1): 28–34. doi:10.1007/s00432-005-0032-1. PMID 16205947. S2CID 25189707.
Latini FR, Hemerly JP, Oler G, Riggins GJ, Cerutti JM (2008). "Re-expression of ABI3-binding protein suppresses thyroid tumor growth by promoting senescence and inhibiting invasion". Endocr. Relat. Cancer. 15 (3): 787–99. doi:10.1677/ERC-08-0079. PMC 2742300. PMID 18559958.
Trynka G, Zhernakova A, Romanos J, Franke L, Hunt KA, Turner G, Bruinenberg M, Heap GA, Platteel M, Ryan AW, de Kovel C, Holmes GK, Howdle PD, Walters JR, Sanders DS, Mulder CJ, Mearin ML, Verbeek WH, Trimble V, Stevens FM, Kelleher D, Barisani D, Bardella MT, McManus R, van Heel DA, Wijmenga C (2009). "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling". Gut. 58 (8): 1078–83. doi:10.1136/gut.2008.169052. PMID 19240061. S2CID 17111427.
Wakoh T, Uekawa N, Terauchi K, Sugimoto M, Ishigami A, Shimada J, Maruyama M (2009). "Implication of p53-dependent cellular senescence related gene, TARSH in tumor suppression". Biochem. Biophys. Res. Commun. 380 (4): 807–12. doi:10.1016/j.bbrc.2009.01.171. PMID 19338757.
Perlis RH, Huang J, Purcell S, Fava M, Rush AJ, Sullivan PF, Hamilton SP, McMahon FJ, Schulze TG, Schulze T, Potash JB, Zandi PP, Willour VL, Penninx BW, Boomsma DI, Vogelzangs N, Middeldorp CM, Rietschel M, Nöthen M, Cichon S, Gurling H, Bass N, McQuillin A, Hamshere M, Craddock N, Sklar P, Smoller JW (2010). "Genome-wide association study of suicide attempts in mood disorder patients". Am J Psychiatry. 167 (12): 1499–507. doi:10.1176/appi.ajp.2010.10040541. PMC 3795390. PMID 21041247.